According to the induced fit hypothesis of enzyme catalysis, which of the following is CORRECT?

Question

A) The binding of the substrate depends on the shape of the active site.

B) Some enzymes change their structure when activators bind to the enzyme.

C) A competitive inhibitor can outcompete the substrate for the active site.

D) The binding of the substrate changes the shape of the enzyme's active site.

E) The active site creates a microenvironment ideal for the reaction.

Answer 1

D) The binding of the substrate changes the shape of the enzyme's active site.

Answer 2

D) The induced fit hypothesis is based on the idea that as the substrate nears the active site, weak attractive forces between the substrate molecule and the amino acids that make up the active site can actually cause a slight conformational change in the active site to make it even more complementary to the substrate.