Am i reading this medical sentence correctly?

Question

It inhibits the secretion of corticotropin-releasing hormone (CRH), resulting in feedback inhibition of ACTH secretion.

- Does that sentence mean that it stops releasing the CRH, resulting in feedback inhibition of ACTH which i believe means that it will produce / secrete more ACTH...

am i right? if not what does that sentence mean in terms that i will understand

Answer 1

I would read 'inhibit' to mean restrains rather than stops entirely (stops it a little?).  Evidently, stopping CRH a little also stops ACTH a little due to feedback inhibition.  However, knowledge of the process is needed to correctly interpret the statement out of context.

Answer 2

it means that it will STOP the secretion of CRH which will then result in ACTH being inhibited as well (via feedback)

feedback inhibition still means inhibition - it's just referring to a particular mechanism

Answer 3

It sounds more like the "it" may be cortisol or another corticosteroid which has negative feedback on the hypothalamus, thereby leading to a decrease in CRH's affect on ACTH secretion.  So I interpret this as a decline in the secretion of ACTH.