At the end of glycolysis, which of the followings is transported to the mitochondria to serve as a....?

Question

starting point for the Krebs cycle?

A. Cytosol

B. Pyruvate

C. Acetyl CoA

D. Oxygen

E. Carbon

Answer 1

C. acetyl CoA

Answer 2

B - it's decarboxylated inside the mitochondria...

link:http://en.wikipedia.org/wiki/Pyruvate_de...

Answer 3

B. Pyruvate

Pyruvate is transported from the cytosol into the mitochondrion after Glycolysis, at the start of the Link Reaction. That is when it undergoes oxidative decarboxylation and CoA is attached to form Acetyl CoA.

But actually the starting material of Krebs cycle is Acetyl CoA. I don't think this would be the answer though, as Acetyl CoA would already be in the mitochondria (product of the Link Reaction).

Answer 4

B. Pyruvate

The outer mitochondrial membrane is permeable to pyruvate. Transport across inner membrane occurs through a specific protein channel (transporter).

In eukaryotic cells, PDH (pyruvate dehydrogenase) complex which converts Pyruvate to Acetyl CoA is present inside mitochondrial matrix.

Answer 5

You know it cannot be a cytosol, oxygen or carbon. Acetyl CoA is in the cycle. Pyruvic acid, B is the starting  point of the Kreb's cycle, since it is a sugar. Glycolysis is a form of fermentation as opposed to respiration. Remember, Acetyl CoA is not PRODUCED via fermentation.