Atherosclerosis?

Question

now im not tt lazy as to ask u to answer this qn.. ;0

just that i wanna ask..Which of the following

types of cells is the initial target in the pathogenesis of this arterial lesion?what does that mean..

i think the answer is endothelial cells..damage to it causes cascade of events leading to plaque formation.any websites to add on this or maybe u have it at the back of your head?

if thats not the answer, then give your intake on this can?

thanks!!

A 50 year old man has a 2 year history of angina pectoris that occurs during exercise.

On physical examination, his blood pressure is 135/75 mm Hg and his heart rate is

79/min and slightly irregular. Coronary angiography shows a fixed 75% narrowing of

the anterior descending branch of the left coronary artery. Which of the following

types of cells is the initial target in the pathogenesis of this arterial lesion?

a. Monocytes

b. Smooth muscle cells

c. Platelets

d. Neutrophils

e. Endothelial cells

Answer 1

I would go with smooth muscle cells.