Question:

Biology Question on Fruit Flies?

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c. Design a series of Drosophila crosses to determine whether or not the locus

for a fictitious gene for a recessive trait for blue wings is on the same

chromosome as the recessive trait for vestigial wings. You can assume that

blue wings and vestigial wings are NOT s*x-linked.

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  1. You would first cross a fly with the normal traits (non-blue, non-vestigial wings, which we'll call C and W) with a fly that has blue, vestigial wings (which would have to be ccww).  Then, in your F1 generation, all of the flies that have normal wings have to be heterozygous for both genes (CcWw) because they got a c and w allele from the recessive parent.

    Okay, so now you have known heterzygous flies.  Do a test cross with them to homozygous recessive (blue, vestigial wing) flies (ccww).  You should expect a 1:1:1:1 phenotypic ratio in the F2 generation.  If your results deviate significantly (which you would determine by doing a Chi-square analysis) from the epected ratio by getting more normal winged and blue vestigial winged flies (over just blue and just vestigial groups), then it means your genes are linked.


  2. haha i remember when i had to do this.. sucks for you ;P

    since it's not s*x linked i think you just have to do regular punnett squares?

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