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Can anyone explain the action of Vitamin D on kidney, bones and intestines?

by Guest57164  |  earlier

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Can anyone explain the action of Vitamin D on kidney, bones and intestines?

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  1. vitamin D helps your body absorb calcium


  2. try this site " http://www.google.co.id/search?hl=id&q=v...  " hope it usefull:)

  3. OK, basically it promotes bone remodelling in the long term - and does this by increasing absorption of calcium  and phosphate which are used in this process.

    Bone - it acts synergistically with parathyroid hormone to promote bone formation

    Kidney - 1. increases reabsorption of Ca2+ and phosphate (compatible with enabling new bone mineralisation),

    2. stimulates increased expression of TRPV5 and TRPV6, calbindin D and NCX in distal collecting tubule and collecting duct cells, and 3. increases expression of type 2 Na+/Pi transporter in proximal straight tubule.

    Gut - 1. increases absorption of Ca2+ and phosphate in small intestine which is caused by the increased expression of TRPV5 and TRPV6 and calbindin D (help in transport)(also increases the activity of existing ATPases in gut which absorb Ca2+). It also increases the type 3 Na+/Pi transporter.

    Sorry if this was more detail that you wanted - you didn't really specify - and I'm revising this topic at the moment so... :)

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