Can we find the cure of aids virus by the virus of cancer?

Question

as we know that cancer virus increase the power of WBC N AIDS VIRUS decrease it. then it can be used to cure aids ...

Answer 1

Its a matter of research

Answer 2

Depends on what the aid is.

Answer 3

Yes,

COLUMBUS , Ohio – Researchers here have discovered how a specific chemotherapy drug helps a cancer-killing virus. The virus is being tested in animals for the treatment of incurable human brain tumors.



Herpes Simplex Virus. Courtesy NASA.  

The virus, a modified herpes simplex virus, is injected directly into the tumor, where it enters only the cancer cells and kills them. The study found, however, that within hours of the injection, infection-fighting immune cells are drawn into the tumor to attack the virus, reducing the treatment's effectiveness.

They also found that a chemotherapeutic drug called cyclophosphamide briefly weakens those immune cells, giving the anti-cancer virus an opportunity to spread more completely through the tumor and kill more cancer cells.

Specifically, the drug slows the activity of immune cells called natural killer (NK) cells and macrophages, which are the body's first line of defense against infections.

The virus and drug cannot be used yet in humans because they require further study, as well as testing for safety and effectiveness through the clinical trials process.

The research, led by investigators with the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, is published in the Aug. 22 issue of the Proceedings of the National Academy of Sciences.



E. Antonio Chiocca

“Our findings suggest that we can use this drug to limit the action of these early responding immune cells, giving the virus time to grow and destroy the tumor,” says study leader E. Antonio Chiocca, professor and chair of neurological surgery and director of OSU's Dardinger center for neuro-oncology.

“They also suggest that the drug may allow us to temporarily inhibit just this early immune response, making it unnecessary to totally suppress the immune system when using this treatment.”

In the late 1990s, a student of Chiocca's discovered that the virus killed tumors more effectively when the animals were first given the drug. Chiocca then set out to learn why.

In this study, one of Chiocca's fellows, Giulia Fulci, now at Massachusetts General Hospital in Boston , examined brains from rats treated with the virus, with and without the drug to identify the immune cells present in the tumor before injection of the virus, and at different times afterward.

Six hours after the injection of the virus, she found that high numbers of NK cells, macrophages and brain-tissue immune cells called microglia had moved into the tumor. The number of macrophages, for example, had risen three fold. In animals given the drug, on the other hand, the number of these immune cells increased by only one half.

Other experiments performed together with Michael A. Caligiuri, director of the OSU Comprehensive Cancer Center , revealed that when the drug is added to NK cells growing in the laboratory, the cells stop making an immune substance called interferon gamma (IFNg). One key effect of IFNg is to attract immune cells to an infection site. The production of the substance could therefore intensify the immune response against the anti-cancer virus.

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“Our findings suggest that we can use this drug to limit the action of these early responding immune cells, giving the virus time to grow and destroy the tumor.”

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Furthermore the researchers found that in rat brain tumors treated with the virus but not with the drug, IFNg levels rose by 10 times after six hours and by more than 120 times after 72 hours. Animals given the drug showed only small increases of IFNg.

Lastly, the researchers tested the treatment in brain tumors in mice that cannot make IFNg. They found that viral genes were expressed much more in these animals.

Overall, the study suggests that cyclophosphamide improves the cancer-killing ability of this virus by inhibiting the activity of NK cells and certain other immune cells and by blocking the ability of cells to make IFNg.

“Over the past decade, cancer-killing viruses have been tested in people as a treatment for cancers of the pancreas and lung, as well as brain tumors, and the viruses have proven to be fairly safe,” Chiocca says.

“One reason these viruses have been so safe may be that they have been so weakened, or attenuated, that they now need help once they are inside tumor cells. One way to help them is to limit the ability of the immune cells that are the body's first line of defense against the virus, perhaps by using this drug.”

Answer 4

No. Your question is not correct. Actually CANCER IS NOT A VIRUS AND IT IS A DISEASE caused by some other virus like HPV and other factors. So treatment of other viruses can not be done as it is. Here one should understand what is cancer or ' CARCINOGENEIS'.

The development of cancer is a complicated process in which a large number of factors interact to disrupt normal cell growth and division. Cancer can be caused by a number of internal factors such as heredity, immunology, and hormones as well as external factors such as chemicals, viruses, diet, and radiation. Although attention is often focused on environmental chemicals (such as asbestos and coal tar) as a cause of cancer, only 5% of cancers can be linked to chemical exposure. We now know that the chief causes of cancer are lifestyle factors such as diet, cigarette smoke, alcohol, and sun exposure. In fact, dietary factors are associated with 35% of all human cancers and cigarette smoke for another 30%.

Whatever the cause of cancer, its development is a multi-stage process involving damage to the genetic material of cells (deoxyribonucleic acid, or DNA). This damage occurs in genes regulating normal cell growth and division. Because several stages or several mutations are required for cancer to develop, there is usually a long latent period before cancer appears.

Carcinogens

Agents that cause cancer (carcinogens) can be classified as genotoxic or nongenotoxic (also referred to as epigenetic). Genotoxins cause irreversible genetic damage or mutations by binding to DNA. Genotoxins include chemical agents like N-methyl-N-nitrosourea (MNU) or non-chemical agents such as ultraviolet light and ionizing radiation. After the carcinogen enters the body, the body makes an attempt to eliminate it through a process called bio transformation (a series of reactions in which the chemical structure of a compound is altered). The purpose of these reactions is to make the carcinogen more water-soluble so that it can be removed from the body. But these reactions can also convert a less toxic carcinogen into a more toxic one. Certain viruses can also act as carcinogens by interacting with DNA.-