Can you develop a tolerance to acetaminophen?

Question

I'm wondering because after 4,000 mg it becomes toxic to the liver i've heard. But i know some people who can take 10 loratabs at a time

Answer 1

Brandon, apples & oranges, son.  Different drug classes.  Hepatotoxicity is not relevant to this.  Tolerance to tylenol is not a big issue.

Answer 2

You can become tolerant to anything if you take it regularly, you can also get neuro poisoning that way. Others have a higher tolerance to different drugs, so they can take more pills with a different effect than someone who had just taken one. So it really all depends on your personal tolerance, but yes if you take it regularly.

Answer 3

I guess they're damaging their liver