Can you take ibuprofen (an NSAID) and bupropion (steroid) if you are taking Entocort (a corticosteroid)?

Question

Abridged interactions from http://fdb.rxlist.com/drugs/drug-22007-Entocort+EC+Oral.aspx?drugid=22007&drugname=Entocort+EC+Oral

This drug should not be used with the following medication because very serious interactions may occur: live vaccines.

If you are currently using the medication listed above, tell your doctor or pharmacist before starting budesonide.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs affecting liver enzymes that remove budesonide from your body (azole antifungals), barbiturates including phenobarbital, cimetidine, HIV protease inhibitors, macrolide antibiotics, rifamycins, St. Johns wort, certain anti-seizure medicines, nonsteroidal anti-inflammatory drugs (NSAIDS such as ibuprofen, naproxen), drugs for diabetes, quinolone antibiotics, drugs that affect the immune system, bupropion, aldesleukin, amphotericin B, mifepristone, licorice (glycyrrhiza).

Answer 1

Just a note. Bupropion is not a steroid. It's a dopamine/norepinephrine based antidepressant drug, frequently used to help people stop smoking. Works in a completely different area of the body.

As for the wether you can take them together. I have no freaking idea. Entocort is a steroid, and I still have nightmares about the abbreviations in that field. This is something you're pretty much going to have to ask the doctor who wrote the prescription for you, because no one else is probably going to know.

Answer 2

As always, you should ask your doctor or pharmacist and not take the advice of people on YA. I am not a doctor or pharmacist.

That said, those three drugs work on entirely different receptors and shouldn't interact. Assuming your liver is healthy and you are on reasonable doses of each drug, you should be okay. However, the previous answer was correct that Bupropion is not a steroid, it is a class of anti-depressant called a dopamine and norepinephrine reuptake inhibitor. It is marketed as an anti-depressant as Wellbutrin, and a smoking-cessation therapy as Zyban.