Casein being broken down by the enzyme trypsin?

Question

hi, I was wondering if anyone could tell me where the protein 'casein' is broken down by trypsin in the human body. Some information on the process would be helpful as well.

Thankyou

Answer 1

See Fig.3 in following paper: http://www.jbc.org/cgi/reprint/259/8/513...

But in this paper researchers used "limited" trypsin digestion. At longer incubation of casein in trypsin solution it will be cut to smaller pieces.

Mechanism of action:

http://article.pubs.nrc-cnrc.gc.ca/ppv/R...

http://chemistry.umeche.maine.edu/CHY252...