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Components of chemical synapse

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can someone describe in detail the components of a chemical synapse between 2 neurons or a neuron and a muscle cell?

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  1. Chemical Synapse

    Transmission is not jumping of action potential but a complex chemical process permitting grading and modulation (frequency change) of neural activity

    Components of chemical synapse:

    Presynaptic neuron - neuron sending the impulse

    Axon of presynaptic neuron terminates on the soma or dendritic region of the postsynaptic neuron

    Axon ends in terminal branches with synaptic k***s that contain many mitochondria and vesicles of a chemical neurotransmitter

    Number of k***s per cell varies, (1-40,000)

    Synaptic cleft - space between cells across which an impulse must be transmitted

    No direct connection, about 20-50 nm space between presynaptic and postsynaptic

    Postsynaptic neuron - neuron receiving impulse

    Neurotransmitter produces the action potential

    Divergence - axon divides into many terminal branches and projects to many postsynaptic neurons

    Convergence - neuron may receive input from thousands of other neurons

    Oscillating circuit - neuron provides positive feedback to presynaptic neurons, prolongs response to stimulus


  2. mostly ECM (Extra cellular matrix) and enzyme.

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