Question:

Could this be a reaction to Lupron?

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I am going to be a surrogate for an infertile couple and their fertility Doc had me administer a Luron Depot (time released over 3 wks) injection on July 18. The last three or four days I have been developing a rash on my face. It isn't very red or even really visible to anyone but me and I even have to look very close and in good lighting. But everyone can feel it when I have them touch it. Its just extremely dry, itchy, and rough. At first it was almost like thousands of tiny flesh colored bubbles covering my chin, cheeks, eye area and corners of my nose. Now it feels scaly and is spreading down under my chin and approaching my neck. It burns when it gets wet and was very painful the one time that I put Benadryl cream on it. It seems to get worse daily.I don't know what caused it. I have never had a reaction to any makeup, cleanser, detergent, or the like. The only thing I can think that is very different that may have caused it is the Lupron.....has this happened to any of you?

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  1. Since you are under close supervision using ART, this would be a question for the nurse coordinator. Give him or her a call right away.


  2.   I would contact your RE about it, especially since it's getting worse. My 1st time on Lupron as a surrogate I didn't have any side effects but the 2nd time I got the same type of rash you're talking about but on my arms. It was very small and not really bothersome though so we kept going. That was almost 5yrs ago and when I get too hot and in winter it *still* shows up.

      I never had the type of Lupron you are on though..mine was daily injections each time.

       Good luck on cycling and your transfer : )

  3. I was on Lupron for 6 months for endometroisis from Aug 07-Jan 08. I had hot flashes and mood swings, but I don't remember ever having any bumps or rashes.

    I'm curious as to why your doc would give you Lupron if you are getting read to be a surrogate. Lupron basically "takes away" the estrogen in your body and tricks your body into thinking you're on menopause so you don't have periods any more. Is that so you won't have periods and risk miscarrying the implanted egg? I've just never heard of it being used for anything except as a management option for endo or prostate cancer in men...

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