Question:

DNA Polymerase III and RNA polymerase II in a cell?

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were do both of these start and stop?

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  1. Well DNA Polymerase III is required during the DNA replication process (during the S-phase of cell cycle - when cells divide). This occurs in the nucleoplasm. The DNA parental strand (double helix) unwind and separates during this process, and numerous DNA polymerase III is attached to these 2 strands at a free 3'-OH end of a primer. It stops when the DNA strand is completely replicated.

    The RNA polymerase II is required during protein synthesis (an entirely different process). The protein synthesis process is made up of  2 process - transcription and translation.

    Transcription is when part of the information on the DNA is transcribed into mRNA strands. This occurs in the nucleoplasm. It occurs because DNA is too large to travel through the nuclear envelope, hence its information has to be "copied" to a smaller molecule (mRNA strand). This process requires RNA polymerase II. The RNA polymerase II binds to the promoter region of a DNA and initiates the transcription process.

    Translation, the second part of protein synthesis, is when the information from the mRNA strand is translated into a polypeptide to form proteins. This process does not include RNA polymerase II but other enzymes.

    Hope this helped!


  2. yes, if a cell have sufficient enzyme s to form a DNA stand, polymerase III will start their work and form either lagging or leading strand.

    leading strand is transcript by RNA Polymerase II & protein will come out.

  3. DNA pol III starts at an 'origin of replication'

    RNA pol II starts at an 'Initiator'

    both of these are specific sequences that help bind the proteins and start replicating (DNA pol III) or transcribing (RNA pol II)

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