Question:

DNA may be altered as a result of ________ events that occur normally in cells?

by Guest10798  |  earlier

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a)depurination

b)deamination

c)depyrimidination

d)all of the above

e)none of the above

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3 ANSWERS


  1. sounds like you have a tough professor.

    I had a professor like that too, his name was Professor Guimond.


  2. Answer = d)

    DNA Damage

    1. Endogenous - originates within the cell; also referred to as Spontaneous.

    2. Environmental - originates from the environment.

    Spontaneous Damage - examples

    1. Mismatches that arise during DNA replication

    2. Damage resulting from the inherent instability of DNA

     incorporation of uracil

     deamination of bases

     depurination and depyrimidination

    3. Oxidative damage

    Environmental Damage - examples

    1. Ionizing radiation produces base damage and strand breaks

    2. UV radiation produces cyclobutane pyrimidine dimers and other photoproducts

    3. Alkylating agents alkylate bases

    http://info.med.yale.edu/therarad/traini...

  3. d) all of the above

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