Describe how red blood cell number is regulated by a negative feedback system. Inlcude the hormone involved?

Question

i need help on this! can't find the answer!

Answer 1

Shouldn't you of learned about this in the classroom where you were given the homework? Or in your textbook? At least check wikipedia.

Answer 2

Erythropoietin (EPO): A hormone produced by the kidney that promotes the formation of red blood cells in the bone marrow. EPO is a glycoprotein (a protein with a sugar attached to it). Human EPO has a molecular weight of 34,000.

The kidney cells that make EPO are specialized and are sensitive to low oxygen levels in the blood. These cells release EPO when the oxygen level is low in the kidney. EPO then stimulates the bone marrow to produce more red cells and thereby increase the oxygen-carrying capacity of the blood.

EPO is the prime regulator of red blood cell production. Its major functions are to promote the differentiation and development of red blood cells and to initiate the production of hemoglobin, the molecule within red cells that transports oxygen.

The EPO gene has been found on human chromosome 7 (in band 7q21). EPO is produced not only in the kidney but also, to a lesser extent, in the liver. Different DNA sequences flanking the EPO gene act to control kidney versus liver production of EPO.

Answer 3

The hormone involved  is erythropoeitin.

I don't know of a negative feed back but everyday  a constant number of RBC are destroyed & an equal number added to the circulation