Question:

Describe how the of ideas and techniques since the 1800's has led to the present success of transplant surgery.?

by Guest5  |  earlier

0 LIKES UnLike

 Tags:

   Report

6 ANSWERS


  1. bite me ben


     


  2. hello


  3. ummm i swear they eat carrot and magic happens


  4. Bleeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeer;D

  5. dunno

  6. By the early 1960s, doctors discovered how to match donor and recipient tissue more closely. They also began to use a combination of radiation (to destroy certain cells) and drugs to suppress the immune system, in effect shutting it down to prevent rejection. These antirejection drugs are called immunosuppressants. As a result of this therapy, the first successful human pancreas transplant took place in 1966. The following year, Thomas Starzl (1926– ) of the University of Colorado performed the first successful liver transplant. (Because of its complicated blood supply, the liver remains difficult to transplant.)

    In 1967, Christiaan Barnard (1922– ), a South African surgeon, received worldwide notoriety for achieving the first successful heart transplant. Barnard took the heart of a young woman and implanted it in Louis Washansky, a 55-year-old grocer. Washansky survived only 18 days. Barnard's second patient, dentist Philip Blaiberg, lived for 17 months.

    The next major advance came in 1972 with the discovery of cyclosporine, an extremely effective immunosuppressant. This drug has proven to be the most effective medicine used to combat the body's own immune system. It has increased survival rates for transplant patients, especially in heart and liver operations.

    Because transplantation of both lungs succeeds better than transplanting a single lung, and because most patients with lung disease also have serious heart deterioration, heart-lung transplants are sometimes performed. The first successful operation of this type was carried out in 1981 at Stanford University Medical Center by Bruce Reitz (1944– ) and Norman Shumway (1923– ).

    In September 1998, in a landmark operation, a team of microsurgeons from four countries spent fourteen hours delicately attaching the forearm and hand from a dead Frenchman to Clint Hallam. The only other reported hand transplant before this took place in Ecuador in 1964, but it had failed because potent immunosuppressant drugs had not yet been developed. The Hallam transplant, however, was doomed from the beginning. Before the operation, Hallam had told doctors he had lost his hand in an industrial accident. The truth was that it had been severed in an accident in a prison in his native New Zealand. After the operation, Hallam agreed to adhere to a physical therapy program to train his new hand and to a regimen of immunosuppressant drugs. But he did neither. Finally, in February 2001, because Hallam's body was rejecting the transplant, a doctor who had helped attach the hand amputated it.

    The lesson doctors learned from this transplant, though, were not lost. Between the end of 1998 and the beginning of 2001, nine other people received new hands in six countries. All were reported doing well. Three of those patients even received right and left hands in double transplants.

Question Stats

Latest activity: earlier.
This question has 6 answers.

BECOME A GUIDE

Share your knowledge and help people by answering questions.
Unanswered Questions