Enzyme glucose-6-phosphatase located

Question

Where is the enzyme glucose-6-phosphatase located?

a) cytosol

b) mitochondria

c) endoplasmic reticulum

d) none of the above

Answer 1

Glucose 6-phosphatase is found in the liver and kidney and is involved in the organs' role in glucose homeostasis. Glucose-6-phosphatase is located on the inner membrane of the endoplasmic reticulum of the liver and kidney. Muscle and brain do not contain glucose 6-phosphatase; as a result any glucose 6-phosphate produced by glycogenolysis is used to generate ATP via glycolysis.

Answer 2

Glucose-6-phosphatase is located attached to the ER in liver cells where gluconeogenesis occurs. It takes glucose -6 -phosphate to free glucose which is then exported to the blood .