Excuse me, too Lazy to Look this Up, but Do the COX-2 Inhibitors Have a Antipyretic Property?

Question

Sock, I Suspect One Could Find a Happy Median.

Answer 1

Well, I would need to check to confirm, but I don't think that COX2s have any antipyresis. I think their increased selectivity decreases ADRs but also their spectrum of usefulness. Thinking more widely, NSAIDS usually do - classically profens (wahey, ibuprofen) and salicylates.

Also, most COX2 specific jobbies are withdrawn or subject to FDA alerts.

Uhm, checked. Yeah, COX2 don't do antipyretic, as far as I can tell for the reason I suggested. And yeah, I just remember reading that some of them had a bit of a ropey history.

Who doesn't love aspirin? I think this would be up to the guys like you, as it'd be very topical - do you want your stomach or your heart to go wrong, and how fast?

Answer 2

They will have a minimal degree of antipyretic properties, but nothing close to acetaminophen.