Has anyone had a baby with Factor V Leiden?

Question

I have Factor V Leiden and 8 PE's and want to know if anyone has had a baby and how it all went?

Answer 1

My friend has Factor V Leiden and I'm afraud she recently lost her baby at 41 weeks.  However she has been told that with daily injections she will be able to carry to term successfully (she was unaware she had the condition until this happened)

There is a petition on the Downing Street web page to routinely screen pregnant women for this, if anyone wants to sign it.

Answer 2

I don't but I have some information from you from sources I rely on to help through pregnancy problems.  

Pregnancy, Clotting, and Factor V Leiden: An Overview

http://www.midwiferytoday.com/enews/enew...

Clotting and Pregnancy Guide

http://www.fvleiden.org/publications/mid...

http://www.midwiferytoday.com/enews/enew...

Riboflavin is a B vitamin. Deficiencies in B vitamins tend to cause higher homocysteine levels, which increase the risk of clotting. In other disorders in which the risk of clotting is high, preeclampsia is also frequent and exacerbated by poor nutritional status. The following study is actually a good confirmation for some of Dr. Brewer's work. Doesn't he advocate eating foods rich in B vitamins during pregnancy, like eggs?

-Jennifer Rosenberg

Riboflavin deficiency can increase the risk of preeclampsia by nearly fivefold in pregnant women already at high risk of developing this complication, according to researchers at University Women's Hospital, Mannheim, Germany. The team examined the link between riboflavin deficiency and preeclampsia prospectively in 154 women already at high risk of this pregnancy complication. The incidence of riboflavin deficiency during the study was 33.8%, where 27.3% of women were riboflavin-deficient at the first antenatal visit and 53.3% were deficient by the last weeks of pregnancy. Riboflavin deficiency increased the risk of preeclampsia with an odds ratio of 4.7. Intracellular free flavin adenine dinucleotide levels were also significantly lower in women who developed preeclampsia than in those who did not. The researchers are in the process of beginning a separate study designed to better test this hypothesis using controlled supplementation. Until these data are available, the authors recommend maintaining normal riboflavin levels in pregnant women. -Obstet Gynecol 2000;96:38-44, via Medscape

There is a lot of controversy over the effectiveness of the Brewer diet during pregnancy, but I find it helpful with morning sickness and dizziness (low blood pressure).  I also had a nearly 42 week pregnancy with zero calcification of the placenta.  I tend to think that while it may do no good it certainly does no harm:

http://www.blueribbonbaby.org

Answer 3

I found out at 13 weeks pregnant that I had a DVT in my right calf and I was put straight onto twice daily injections of Enoxaprain (Clexane in some countries, Lovenox in others) until I went into labour. I carried to term and then some and had a healthy 9lb 3oz baby who is now 3 months old. After delivery I had to take Warfarin for 12 weeks and I am now on my 6 week break before I start test for Factor V Leiden and Thrombophillia (as I had a CVA in my brain at 18 also) and I am almost certain that the test will come back positive. Anyway, it's not completely relevant to you as your condition is diagnosed but my pregnancy went well, the injections weren't very nice but the end result is amazing.