Question:

How does Egg donation work?

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I guess I'm wondering how egg donation works...Is it painful? Please just give me all the information you have on this! I'm not doing it but I am interested in how it goes. Maybe sometime I can donate my eggs to a woman in need! Serious answers only!

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  1. You will be given intravenous anesthesia and the doctor will use a vaginal ultrasound to guide a thin needle into the ovarian follicles. Fluid containing eggs is removed with gentle suction and examined at the Center's IVF laboratory. Mature eggs are removed from the fluid. Following exposure to the husband's/partner's sperm, the egg(s) is/are fertilized. The resulting embryo(s) is/are monitored in the laboratory for five days before one or two of the resulting embryos are placed into the recipient’s uterus.

    YES ITS PAINFUL!


  2. Well

    Egg donation carries risks for both donor and recipient. The egg donor may suffer complications from IVF, such as bleeding from the oocyte recovery procedure and reaction to the hormones used to induce hyperovulation (producing more than one egg), including ovarian hyperstimulation syndrome (OHSS) and, rarely, liver failure[2]. The long-term impact of egg donation on donors has not been well studied, but apparently some evidence suggests a risk of early menopause and increased risk of ovarian cancer[3].

    According to Jansen and Tucker, writing in the same ART (assisted reproductive technologies) textbook referenced above[4], the risk of OHSS varies with the clinic administering the hormones, from 6.6 to 8.4% of cycles,half of them "severe." Patients treated with GnRH agonists appear to be at increased risk compared to those treated with GnRH antagonists. The most severe form of OHSS is life threatening. One study in the Netherlands found 10 documented cases of deaths from IVF, with a rate of 1:10,000. "All of these patients were treated with GnRH agonists and none of these cases have been published in the scientific literature." Hormone treatments that can be dangerous in the short-term may have long-term health effects.

    Daniel Navot, writing in the same collection of reports states that mild OHSS is a sign that treatment is working and describes the symptoms of moderate OHSS as "includes significant ovarian englargement (5-12 cm)...abdominal pain, significant bloating,nausea, and diarrhea," symptoms attributable to ovarian enlargement and elevate estrogen levels. Signs that upgrade moderate OHSS to the severe form include liver dysfunction and anasarca. Criteia for severe OHSS include enlarge ovary, ascites, hemotacrit > 45%, WBC > 15,000, oliguria, creatinine 1.0-1.5 mg/dl, creatinine clearance > 50 ml/min, liver dysfunction, anasarca. Critical OHSS includes enlarged ovary, tense ascites with hydrothorax and pericardial effusion, hematocrit > 55%, WBC > 25,000, oligoanuria, creatinine > 1.6 mg/dl, creatinine clearance > 50 ml/min, renal failure, thromboembolic phenomena,ARDS.

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