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How is a spindle formed in prophase?

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  1. a spindle is formed in prophase when two cells unite each other


  2. During prophase the chromosomes are identical chromatids connected at the center by a centromere, forming a X-shaped object. The distinguishing feature of prophase is the setup of the mitotic spindle, which is used to maneuver the chromosomes about the cell. The spindle is formed by excess parts from the dismantled cytoskeleton. The spindle is initially setup outside the nucleus.

    The cell's centioles are duplicated to form two pairs of centrioles. Each pair becomes the part of the mitotic center which forms the focus for an array of microtubules, called the aster. The two asters lie side by side close the the nuclear envelope. Near the end of prophase the asters pull apart and the spindle is formed.

  3. Microtubules are made up primarily of a globular protein known as tubulin.  Many tubulins stick together to form a microtubule.

    The mitotic spindle is made up of microtubules that originate from the microtubule organizing centers (MTOC).  MTOCs are at the kinetochores in the centromeres of the chromosomes, the others at the so-called poles of the nucleus.  In animals and some fungi, the poles have centrioles.  In plants, however, there are no centrioles at the poles.

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