How many pilots EWR-HNL and HNL-EWR requires?

Question

This is perhaps the longest domestic nonstop route in North America and in the world both in time and distance.

Answer 1

Three, two working at any one time and one as a  relief pilot.

Answer 2

It is probably the longest domestic route actually flown, but Newark to Agana, Guam would be much longer- 7950 v 4956 miles.

Regards,

Dan