How would a small hole in the heart affect the oxygen content of blood pumped to the body?

Question

Additional details:

1. The hole is between the left and right ventricle.

2. Let us consider the case of a newborn baby.

Answer 1

not sure.  perhaps the blood pressure is compromised.  the heart is pumping but the pressure is poor and doesnt allow good flow of blood through the body (hence, poor oxygenation throughout the blood stream)  

kind of like a vaccuum with a hole/leak in it.  the suction isnt good so no little or no pressure

Answer 2

The blood from right ventricle goes into pulmonary arteries&

The blood from left ventricle goes into Aorta

If the hole is between the left and right ventricles   problem

arises  during systole[contraction]of ventricles.

The left ventricle being at higher pressure causes the blood to flow into the right ventricle and only less amount of blood flows into the aorta.

This causes overload on the right heart and indirectly on the pulmonary vascular bed.

This may lead to pulmonary edema &pulmonary hypertension which are fatal

Answer 3

With a small hole between the left and right ventricle, the oxygenated blood and oxygen-depleted blood will freely mix.  So, on average, the blood pumped to the body would be bringing less oxygen, since it's recirculating some that hadn't taken a trip to the lungs since its last trip around the body.

Most "reptiles" have three-chambered hearts, and mix their blood this way all the time.

The four-chambered heart evolved at least twice from reptiloid ancestors, in the lines leading to the crocodiles (which also led to dinosaurs and birds);  and the line leading to mammals.  Having the dual-circulation system separating oxygenated from oxygen-depleted blood is more efficient, and probably a requirement for a high metabolism as warm-blooded creatures have.

A person with this kind of heart defect would have the outward symptoms of anemia -- tiring easily, shortness of breath.

Fortunately, the defect can be corrected with surgery.

Answer 4

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