I Just Saw an Ad By Bayer for "Heart Advantage". Overstated Cholesterol Lowering?

Question

You Will Note, Bayer's Recommend Dose of 800 mg is 20% Lower than the Lowest Effective Dose In the Study.

Answer 1

It strikes me as a fairly plausable piece of pharmacological reasoning - using plant-derived man-like antagonists to block receptors and therefore stop transport of potentially harmful compounds into the body.

However, I have absolutely no idea of how effective it could be. I think the receptors are mediated by far too complex a mechanism for this to be the sole factor. The pharmacokinetics and dynamics are probably variable at best. I imagine this is scientific research with a bolus of i.v. hubris at some point.. pardon my attempt at humor.

Answer 2

The dose of ASA is not specified. IF, 81 mg/pill, 2/pills a day would be double the dose of low-dose ASA. So, taking unnecessary asprin daily? Not so good as far as the potential for gastric bleeds or hemorrhagic strokes are concerned.

The study also clearly indicates that between 1-3 g/day of phytosterols can effectively lower cholesterol. Bayer recommending that the consumer take 400 mg twice a day for effect is probably equivalent to eating a pile of sand for cholesterol.

The product can not do what it claims to do. Period. Another scam.

EDIT: Yeah, it appears that greed and money wins out...

EDIT 2: Opps, yup, that's what I meant. I've changed it in the above.

Read the wikipedia attachment. Pretty conistent with the above.

EDIT 3: Yeah, maybe. One can't be sure, though. There are many nonsense reasons people do this...In any event, it doesn't affect me :-) :-).