I am seriously considering of doing a remake of the movie "What's Up, Doc?". Who could play the leads?

Question

Barbara Streisand and Ryan O'Neil originally played characters Judy Maxwell and Doctor Howard Bannister. Who would be great actors of today that could reprise these roles?

Answer 1

 Ever since the finale of Friends I've had this thought. Get these cast members back together in a non-friends movie. Their chemistry is just too good for it not to work.

Jennifer Aniston - Judy Maxwell

David Schwimmer - Howard Bannister

Courteney Cox - Eunice Burns

Matthew Perry  & Mat LeBlanc as the two Spies

Lisa Kudrow - Mrs. Van Hoskins

Of course the plot would have to be tweaked a little in order for Perry, LeBlanc & Kudrow to get more screen time, but it's make a killing at the box office.

Good luck. I love this movie. It needs an update for a new generation.