If a patient had an over intake of Na Bicarbonate drug, what will happen to the pH of the blood?

Question

If a patient had an over intake of Na Bicarbonate drug, what will happen to the pH of the blood?

Answer 1

The pH will increase (become more alkaline). pH is a measure of hydrogen ions (H+). More H+ = more acid. Bicarbonate likes to mop up H+ ions - it is the main buffer in the body. To a certain extent your body could compensate by not breathng out so much CO2. Extra CO2 in the blood makes it more acid, so this would balance things out a bit.

Answer 2

the blood has buffer mechanism wich act at blood (proteins, phosphates) level, respiratory level n renal level to keep pH of blood normal.

howvever if the intake is beyond the capacity of buffers, it will lead to metabolic alkalosis i.e alkaline pH of blood.

this will lead to gastrointestinal disturbance causing vomiting, adrenal-cortical hyperfunction and alkali intoxication!person can go into shock n needs to be hospitalised!