In Bone Formation?

Question

A deficiency of growht hormone will cause:

inadequate calcification of bone

decreased osteoclasts activity

increased osteoclast activity

decreased proliferation of the epiphyseal plate cartilage

Answer 1

Growth hormone deficiency causes decreased proliferation of the epiphyseal growth plate. (see attached article under hormones acting on bone tissue)

http://books.google.com/books?id=lYHBfPf...

P.S- Growth hormone does not have any effect on calcification of bone. The latter is controlled by other hormones viz. parathyroid hormone, vitamin D and calcitonin (last one secreted by thyroid).

Answer 2

it will decrease proliferation of the epiphyseal plate cartilage

Increase osteoclast activity and decrease osteoclast activity aren't affected by GH

Inadequate calcification of bone has to do with bone density.