In area, what is the largest city in the largest county in the largest state east of the Mississippi River?

Question

In area, what is the largest city in the largest county in the largest state east of the Mississippi River?

Answer 1

Going by land area (not including water rights held by vaiours states), Georgia is the largest state.  See: http://en.wikipedia.org/wiki/Georgia_(U.S._state)

Ware County is the largest county, land area-wise.

Waycross is the largest city in Ware County.