Ipratropium general questions! Please help!?

Question

Hello, I am doing this assignment and I cannot find ANY information pertaining to ipratropium. I need info on what plant it can be found in, a retail selling price, company that produces it, discovery of it (who where when) etc. Any help (especially about the plant part) would be greatly appreciated.

Answer 1

It appears that ipratropium is synthetic, not from a plant.

"The medicinal properties of naturally occurring anticholinergic agents such as atropine, found in many plants in the tropics and temperate climates, have been recognized for centuries. There are reports from India dating from the 17th century that describe the use of Datura stramonium leaves for the treatment of asthma from the 17th century. This plant arrived in Europe by the 19th century via British colonialists and was used to treat a wide assortment of breathing disorders.5 The anticholinergic agents, such as atropine and scopolamine, are readily absorbed from the respiratory and GI tracts and have significant side effects. Newer synthesized agents, such as ipratropium bromide, oxitropium bromide, and tiotropium bromide, have similar but modified chemical structures compared with naturally occurring anticholinergics. "

Without a drug plan, an inhaler costs between $30-50 and is good for 200 doses.

The second link is to a company that makes the "Combivent" inhaler--a mixture of ipratropium and albuterol.

Answer 2

talk to a pharmacist.

Answer 3

Ipratropium bromide (Atrovent) is a synthetic  anticholinergic agent with properties similar to naturally occurring atropine (belladonna / deadly night shade.)  The anticholinergic effects thicken and dry secretions and slow down your GI tract. The nice advantage of ipratropium bromide is that it is a quaternary ammonium ion (charged), therefore it does not cross membranes and will not readily cause the systemic side effects found with atropine.

Atropine overdose - red as a beet (vasodilation), hotter than h**l (hyperthermia), madder than a hatter (hallucinations), faster than a rabbit (rapid heat beat).

Atrovent is an inhaler and can be used for a number of treatments.  Similar agent with similar properties is glycopyrrolate - can be used in a tablet form for a spastic gut.

Best of luck!

Answer 4

ipratropium is created synthetically in laboratories