Irreversible and reversable cell injury, what are their meanings?

Question

I need to find out the meanings of both irreversable and reversable cell injury and how they differ.

Can you please help.

Answer 1

Reversible cell changes are responses to injuries of low intensity and/or short duration. They are recognized by subtle changes in cell structure and/or the accumulation of some material in the cytoplasm. These changes take time to develop and are preceded by biochemical and EM changes. By the time cellular responses to injury are detected with the LM, they are far along in their development.

Reversible cell injuries tend to affect actively functioning cells rather than quiescent ones. Absorptive and secretory epithelial cells are more vulnerable than connective tissue cells; put in scientific terms, parenchymal cells are more commonly affected than stromal cells.

Irreversible Cell Damage— Cell “death” is called “necrosis.” Necrosis is, of course, irreversible—a dead cell cannot return to life. Some cells are more susceptible to necrosis than others. Cells lining kidney tubules and the intestines are very

susceptible to necrosis. Other cells can withstand damage much better. see link