My notes say it's coupled to RNA polymerase alpha to start transcription, etc in prokaryotes, but on a take home test the question asks:
"A mutation in the sigma subunit of DNA polymerase δ causes it to remain tightly bound to the holoenzyme at all times." (Then we say what would happen in the scenario.)
Is the DNA pol. δ what part of the sigma subunit is part of? (Is it part of DNA pol, but "helps out" RNA pol.?) And I thought that DNA polymerase δ was specific to only prokaryotes (and DNA pol II was it's eukaryotic equivalent)....how is it in a bacterium/prokaryote then? I have a feeling she may have messed up what she told us in class, but unfortunately it's not in the book. I'm trying to figure out if it's a trick question or if that's how it was supposed to be.
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