Is urea a component of DMSO?

Question

Is urea a component of DMSO?

Answer 1

Dimethyl sulfoxide (DMSO, RIMSO-50) was the first of two therapies approved by the US FDA for the treatment for IC in the early 1970's. Its use has quickly diminished due to the growing popularity of rescue Instillation's and research that suggests that DMSO can be damaging to the bladder muscle. Many clinics no longer use DMSO treatments.

IT ISN"T A GOOD IDEA to have DMSO Tx in my opinion, I had them, made it worse then before! It burns the bladder, and originally was used on animals! If your question relates to having treatments, I strongly suggest to get a second opinion, but if it is for lab testing/experiments, I doubt it very seriously, a waste product of urine would be part of a compound placed into the bladder. I'm saying "no" from what I know. :o)

DMSO is a dilute, sterile, and purified version of a chemical that was used for many years as an industrial solvent before being found to have anti-inflammatory, analgesic, muscle relaxant, mast cell stimulation and collagen dissolution properties.

Urological Association suggests that DMSO may cause damage to the muscle of the bladder when used at the 50% dosage.

In "DMSO - Does it change functional properties in the bladder wall"  researchers tested various concentrations of DMSO on strips of bladder muscle to try to determine what, if anything, the DMSO did to muscle.

They found that DMSO triggered intense muscle contractions and, at doses higher than a 30% solution, caused what appeared to be long-lasting contractions that could be irreversible.

Since the normal FDA approved dosage used for humans is 50%, researchers suggested that the dosage be reduced to, at most, 25% to avoid any possibility of muscle damage.

It is dissolved in blood and excreted by the kidney as a component of urine. In addition, a small amount of urea is excreted (along with sodium chloride and water) in sweat.

UREA is a waste product, I doubt it would be part of a DMSO cocktail for humans, but maybe in animals it may have some purpose?

Answer 2

No. And FWIW, DMSO has a big hazard warning on it that says:

"MSDS recommends wearing safety glasses because DMSO can cause chronic damage to the eyes.[9] Glove selection is important when working with DMSO. Thick rubber gloves are recommended."

Answer 3

No, but the compounds are similar. Urea is a s double bonded to an O, and flanked by two nh2 (amine) groups. DMSO is flanked by two methyl groups instead.