Location, Synthesis, Stimulus, Function of ADH (vasopressin)?

Question

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Answer 1

Anti-Diuretic Hormone

Location= Posterior Pituitary gland of the Hypothalamus

Synthesis= secreted as a Primary Hormone (along with the hormone oxytocin) directly into the systemic circulation

Stimulus= Low blood volume, pain, trauma, stress, nicotine, morphine, tranquillisers

Inhibition= Dilute plasma, alcohol

Function= 1)Promotes water re-absorption in the collecting duct, which increases blood pressure & blood vol

2) Causes vasoconstriction during severe haemorrhage

Notes= Hormone replacement therapy is administered by nasal spray

Auto-immune destruction of the paraventricular cells of the hypothalamus leads to diabetes insipidus