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Question

It's a fairly recent release, on dvd anyway. The preview shows a city full of mutant types who were locked away after some sort of disease, and a girl who has to go there for some reason. Lots of explosions and such.

Hope this is enough to go on! Thanks in advance!

Answer 1

Doomsday.

It's awesome, go see it.

Answer 2

Doomsday

Answer 3

More detail would help.  In addition to the other guesses, that sounds like it could also be 28 Weeks Later.

Answer 4

what like a resident evil sort of thing??  

Answer 5

Is it Resident Evil Extinction?