Medical Implication in meiosis???

Question

What is the medical implication of when meiosis occurs in human females? That is what illnesses, diseases or conditions can result from this and why?

thanks so much!!!

Answer 1

many of them

1-chromosomal disjunction which means that the chromosomes fail to separate in the metaphase which leads to monosomy(2n-1)(egg or oocyte with only one Chromosome  and if the deficient  was in autosomal chr. it won't be compatible with life but if it was in s*x chromosome (it will make) it as in Turner syndrome.

and trisomy(like Down syndrome)(2n+1)

2-Deletions: A portion of the chromosome is missing or deleted so as you know that this portion may have the genetic material that will be responsible for production of important proteins,enzymes,cancer suppressant......etc which will lead to disease caused by the deficiency of this or that enzyme.

3-Translocations: When a portion of one chromosome is transferred to another chromosome which happens in what is called Philadelphia chromosome here there will be translocation from chrom. no 9 to chrom.no22 and that's will lead to cancer disease called myleoid leukemia and the mechanism of that the portion of chromosome was suppressed by neighbor portions so that it will not be translated as materials that cause cancer(growth factor for example)and when it's transferred it won't be suppressed by his neighbors and it will make troubles.

indeed there are many other types of chromosomal abnormalities like inversion .....etc you can check for them

you can search for this subject by words like aneuplody and polyplody ,chromosomal abnormalities something like that.regards