Other than insulin, what can a genetically altered bacterium produce?

Question

I did a biology exam earlier on today and there was a question asking this, it gave 3 answer boxes, i randomly said rennin cause i couldn't remember

Answer 1

Bacteria can be used to express most proteins. They are not always the expression medium used for commercial production but they are often used in the lab for quick growth and easy expression. I used them to do all subclone construction into expression vectors after cloning unknown genes from large gene families. Before the human genome project the idea was just to get the genes out then find out what the protein did by cell expression assays that bound protein ligands. To publish all we needed was to name cell source and binding function for the protein in vitro. Working in cytokines meant we needed to assay cell types in surface binding flow cytometry assays.

For production expression was in bacteria for granulocyte macrophage colony stimulating factor (GM-CSF), & hTNFalpha conveting enzyme (TACE)

The  production  of recombinant proteins (e.g. therapeutic proteins) in E. coli has problems. The  formation  of  insoluble inclusion  bodies  is a frequent consequence of high-level protein production. Also, the purification of the soluble protein  from the bacteria's cytoplasmic proteins is relatively difficult.