Question on clinical investigations?

Question

Q. A clinical study is performed to assess treatment out comes in patients who have macrocytic anemia.A comparison of laboratory testing strategies shows that the best startegy is to test for both B12 and Folate levels.What is the most important reason for obtaining the results for both B12 and folate?

1.Both nutrients are absorbed by a similar mechanism

2.Both nutrients are needed for DNA synthesis

3.Multilobed neutrophils occur with deficeincy of one but not the other.

4 Aplastic anemia can occur with deficiency of either.

5.Spinal cord injury occurs with deficiency of one but not the other.

Answer 1

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