Human Height Growth - Please explain?

Question

I'm confuse.. how does it work

Answer 1

Am not sure..

Answer 2

Growth hormone (GH) is a hormone that stimulates growth and cell reproduction in humans and other animals.

When GH is secreted into the bloodstream by the pituitary gland, it induces the production of another hormone, called Insulin-like Growth Factor 1, or IGF-1.  Cells that are capable of growth (i.e. cell division and proliferation) have receptor molecules attached to the cell membrane which can detect the presence of signaling molecules in the body.  Just as you have to have the right equipment to receive and process a radio, TV, or satellite signal, a cell must have the correct molecular receptor to receive a specific  signal. Once a cell receives the IGF-1 signal, the cell is stimulated to divide,

and thus growth occurs.  In a normal system, IGF-1 and GH levels help to regulate each other:  For example, when IGF-1 levels are high, production of GH is reduced.

During childhood, and through puberty, the long bones of the body contain epiphyseal plates, commonly called “growth plates”. These are populations of cartilage cells, which are located at each end of the bone. The cartilage cells, called chondrocytes, are very responsive to the growth signals present in a normal growing body and continue to divide, which enables the bones to keep on growing until the person reaches their adult height. Once this height is reached, the cartilage in the epiphyseal plates is replaced by rigid bone, which does not respond to GH.  

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