Sickle-cell anaemia is caused by?

Question

Sickle-cell anaemia is caused by?

Answer 1

Not having enough iron in body

Answer 2

genetics? i don't know

Answer 3

when a person inherits two abnormal genes that cause their red blood cells to change shape

Answer 4

Low Iron like me or just ask your Dr.

Answer 5

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Answer 6

genetics

Answer 7

Sickle cell anaemia is caused by a defect in the haemoglobin molecule that is found in the red blood cells that carry oxygen.

Haemoglobin is a protein molecule. It consists of 4 chains- 2 alpha and 2 beta chains. Proteins are 'custom made' by the cells by joining different amino acids in a specific order.

The structure of a specific part of DNA in the nucleus of the cell determines the order in which amino acids are joined.

The only difference between normal haemoglobin and sickle-cell haemoglobin is in the 2 beta chains of the molecule. At a place where there should be the amino acid 'Glutamic acid' there is the amino acid 'Valine'.

This error is caused by a 'mutation' or change in the structure of the DNA that codes for the amino acid 'glutamic acid'

Sickle cell anaemia is caused by a genetic mutation.

The faulty haemoglobin causes the red blood cell to be sickle-shaped instead of 'a biconcave disc shaped'

Answer 8

Genetics-Sickle-cell conditions are inherited from parents in much the same way as blood type, hair color and texture, eye color and other physical traits.

Sickle-cell disease or sickle-cell anaemia (or anemia) is a blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in their restricted movement through blood vessels, depriving downstream tissues of oxygen. The disease is chronic and lifelong: individuals are most often well, but their lives are punctuated by periodic painful attacks and a risk of various other complications.

Sickle-cell disease occurs more commonly in people (or their descendants) from parts of the world such as sub-Saharan Africa, where malaria is or was common, but it also occurs in people of other ethnicities.Sickle-cell disease or sickle-cell anaemia (or anemia) is a blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in their restricted movement through blood vessels, depriving downstream tissues of oxygen. The disease is chronic and lifelong: individuals are most often well, but their lives are punctuated by periodic painful attacks and a risk of various other complications.

Sickle-cell disease occurs more commonly in people (or their descendants) from parts of the world such as sub-Saharan Africa, where malaria is or was common, but it also occurs in people of other ethnicities. This is because those with one or two alleles of the sickle-cell disease are resistant to malaria since the sickle red blood cells are not conducive to the parasites - in areas where malaria is common there is a survival value in carrying the sickle-cell genes.

Answer 9

Sickle cell anemia is a genetic disorder.

Answer 10

Gene mutation.