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The restriction enzyme Smal cuts DNA at the 6-base recognition sequence 5'-CCCGG-3'.?

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Calculate the frequency of occurrence of this sequence.

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  1. If we assume that all bases are equally abundant and so have an equal chance of occurring at any locus, then:

    (1/4 ) ^6 if it is a 6 base sequence.  This is 0.000244, or 1 in 4096 random 6-base sequences

    You have only included 5 bases in your stated sequence, and it's not palindromic, so you may want to check on that.

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