To much protein in urine?

Question

what is the coarse of having to much protein in urine

Answer 1

Proteinuria is often diagnosed by a simple dipstick test although it is possible for the test to give a false negative even with nephrotic range proteinuria if the urine is dilute. False negatives may also occur if the protein in the urine is composed mainly globulins or Bence-Jones Proteins because the reagent on the test strips, Bromphenol blue, is highly specific for albumin. [5][6] Traditionally dipstick protein tests would be quantified by measuring the total quantity of protein in a 24-hour urine collection test, and abnormal globulins by specific requests for Protein electrophoresis.[7][8]

Alternatively the concentration of protein in the urine may be compared to the creatinine level in a spot urine sample. This is termed Protein/Creatinine Ratio (PCR). The 2005 UK Chronic Kidney Disease guidelines states that PCR is a better test than 24 hour urinary protein measurement. Proteinuria is defined as a Protein:creatinine ratio >45 mg/mmol (which is equivalent to Albumin:creatinine ratio of >30 mg/mmol) with very high levels of nephrotic syndrome being for PCR > 100 mg/mmol.[9]

[edit] Associated conditions

Proteinuria may be a sign of renal (kidney) damage. Since serum proteins are readily reabsorbed from urine, the presence of excess protein indicates either an insufficiency of absorption or impaired filtration. Diabetics may suffer from damaged nephrons and develop proteinuria. The most common cause of proteinuria is diabetes and in any person with proteinuria and diabetes the etiology of the underlying proteinuria should be separated into two categories: diabetic proteinuria versus the field.

With severe proteinuria, general hypoproteinemia can develop which results in diminished oncotic pressure. Symptoms of diminished oncotic pressure may include ascites, edema, and hydrothorax.

[edit] Conditions with proteinuria as a sign

Proteinuria may be a feature of the following conditions:[6]

Nephrotic syndromes (i.e. intrinsic renal failure)

Pre-eclampsia

Eclampsia

toxic lesions of kidneys

Collagen vascular diseases(e.g., systemic lupus erythematosus)

Dehydration

Glomerular diseases, such as membranous glomerulonephritis, focal segmental glomerulonephritis, minimal change disease (lipoid nephrosis)

Strenuous exercise

Stress

Obsessive Compulsive Disorder

Benign Orthostatic (postural) proteinuria

Focal segmental glomerulosclerosis (FSGS)

IgA nephropathy (i.e., Berger's disease)

IgM nephropathy

Membranoproliferative glomerulonephritis

Membranous nephropathy

Minimal change disease

Sarcoidosis

Alport's syndrome

Diabetes mellitus

Drugs (e.g., NSAIDs, nicotine, penicillamine,gold, ACE inhibitors, antibiotics, opiates especially heroin.[10]

Fabry's disease

Infections (e.g., HIV, syphilis, hepatitis,post-streptococcal infection)

Aminoaciduria

Fanconi syndrome

Heavy metal ingestion

Hypertensive nephrosclerosis

Interstitial nephritis

Sickle cell disease

Hemoglobinuria

Multiple myeloma

Myoglobinuria

Organ rejection- kidney transplant patients may have gamma-globulins in their urine if the kidneys start to reject.[11]

Ebola hemorrhagic fever

Nail Patella Syndrome

Familial Mediterranean fever

HELLP Syndrome

Answer 2

Wow, even the second A. is mighty long.

To much protein in urine in young people is caused by heavy exercise or cold. Short of having a disease, you shouldn't worry to much.

Answer 3

The above answer was fantastic reading for me, but simply put, if you are young and athletic and have protein in your urine, most doctors don't worry about it that much.  

It could be that you were hungry that day, and just exercised.  You could have also been dehydrated.  Stress is a big cause of this as well.  You may just need to go in for a repeat UA in a month or so and be sure to not work out that morning, or go in starving.  

If the problem persists then they may send you to a Urologist for further evaluation.  They would place a cystoscope up your bladder that takes a microscopic view of the inner lining of your bladder to determine if the proteins are from inflammation in your bladder or if the problem is further up in your kidneys.  

If the problem is in the bladder you may need to avoid foods that irritate the bladder such as the ones mentioned in this article:

http://www.kitchentablemedicine.com/diet...

If your doctor isn't too worried about it, then you probably should just ask to be re-checked at your next visit.  And that is based off the assumption that you are perfectly healthy, without any prior health complaints.  

Hope that makes a little better sense hun.  Take care.