Question:

Unisom sleeptabs after a day of drinking?

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i got pretty drunk today (drank at 2 30- 3 pm) and it is now 10 pm. i feel more or less normal, just a little bit "off".

i have unisom sleeptabs (25mg doxylamine succinate)- is it safe to take them tonight, maybe in an hour?

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  1. Yeah you'll be fine. Alcohol is a GABA agonist and lasts up to about 8 hours max and is metabolized by ADH enzyme. Doxylamine is infact an anti-histamine (H1 antagonist) and causes sedation by reducing acetylcholine in the brain and is metabolized by CYP2D6 enzyme, so yeah no interaction, your fine!

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