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Unresolved Q#4 ? " All Non-steroidal anti-inflammatory drugs are highly interactive with aspirin " Why? Doctor

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  1. NSAIDs contains salicylic acid as a metabolite of aspirin.


  2. If a COX-2 inhibitor is taken, one should not use a traditional NSAIDs. NSAIDs can be broadly classified based on their chemical structure. NSAIDs within a group will tend to have similar characteristics and tolerability. There is little difference in clinical efficacy among the NSAIDs when used at equivalent doses. The differences among compounds tended to be with regards to dosing regimens (related to the compound's elimination half-life), route of administration, and tolerability profile. Patients on daily aspirin therapy (as for reducing cardiovascular risk or colon cancer risk) need to be careful if they also use other NSAIDs, as the latter may block the cardioprotective effects of aspirin.

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