Vitamin B6?

Question

Can I take in 100mg or 200mg everday or will that lead to neuropathy in the future?

If so, when are the best times to take in 100mg or 200mg of b6?

Answer 1

Sounds like 100mg is ok.

Too much vitamin B6 can result in nerve damage to the arms and legs. This neuropathy is usually related to high intake of vitamin B6 from supplements, [28] and is reversible when supplementation is stopped. According to the Institute of Medicine, "Several reports show sensory neuropathy at doses lower than 500 mg per day" [12]. As previously mentioned, the Food and Nutrition Board of the Institute of Medicine has established an upper tolerable intake level (UL) for vitamin B6 of 100 mg per day for all adults [12]. "As intake increases above the UL, the risk of adverse effects increases [12]."

Answer 2

The ingestion of megadoses (> 500 mg/day) of pyridoxine (eg, taken to treat carpal tunnel syndrome or premenstrual syndrome although efficacy is unproved) may cause peripheral neuropathy with deficits in a stocking-glove distribution, including progressive sensory ataxia and severe impairment of position and vibration senses. Senses of touch, temperature, and pain are less affected. Motor and central nervous systems are usually intact.

Diagnosis is clinical. Treatment is to stop taking vitamin B6. Recovery is slow and, for some patients, incomplete.

http://www.merck.com/mmpe/sec01/ch004/ch...