What are messages about tissue damage up by and where does it transmit?

Question

What are messages about tissue damage up by and where does it transmit?

Answer 1

Picked up by receptors and transmitted to the spinal cord via small, myelineated fibers and very small unmyelinated fibers. From the spinal cord, the impulses are carried to the brainstem, the thalamus and cerebral cortex and ultimately perceived as pain. These messages can be suppressedd by a system of neurons that originates in the gray matter of the midbrain called "Descending System."