Question:

What are the effects of sedatives on muscle tissue?

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If a syringe filled with a sedative that was meant for intravenous use was somehow injected into a muscle instead, what would happen to the person? Would they still fall unconscious or close to? Would that particular muscle simply cease to be effective until the average time the sedative would wear off? Would it be completely ineffective? Thank you in advance.

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  1. Almost all intravenous medication including sedatives if accidentally given into muscles work late but the same way as IV. Muscles are not effected.


  2. We give some sedatives that way.  It depends on the drug.  It is an acceptable way to give many sedatives, including midazolam, diazepam, morphine, demerol, ketamine, and others.

    The drug would still be absorbed in the systemic circulation, just at a slower rate.  It would not affect the muscle directly, unless it was a formulation that was extremely acidic or (more likely) basic, and then you might get some irritation at the injection site.

  3. This depends greatly on the specific type of sedative. Benzodiazepine? Barbiturate? Muscle relaxer? Opiate? Dissociative?...

    Generally speaking, IM injections are more of a slow-release method than IV. That's about all the advice you are gonna get here without supplying more info.

    Some preparations intended specifically for IV use could potentially have myotoxic efficts if you shoot it in your arm or butt.

    Long story short, if you are asking this question here, you probably shoudn't be s******g around with needles

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