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What are the side effects of overdosing on asprin?

by Guest63292  |  earlier

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What are the side effects of overdosing on asprin?

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  1. Bad on stomache.


  2. Liver failure, internal GI bleeding, death, to name a few.

  3. ulcers, and excessive bleeding in ur stomach & also i've been told that it is a blood thinner

  4. totally thins your blood out.  Will kill your liver.

  5. It doesn't say on the bottle?

  6. well if you have mild intoxication, you most likely will have nausea, abdominal pain and feel dizzy. severe poisoning can lead to hallucinations, comas, and hypoglycemia to name a few. either way you should definitely see a doctor.

  7. why OD on asprin

  8. Overdose

    Aspirin overdose can be acute or chronic. In acute poisoning, a single large dose is taken; in chronic poisoning, supratherapeutic doses are taken over a period of time. Acute overdose has a mortality rate of 2%. Chronic overdose is more commonly lethal with a mortality rate of 25%; chronic overdose may be especially severe in children.[79]

    [edit] Symptoms

    Aspirin overdose has potentially serious consequences, sometimes leading to significant morbidity and mortality. Patients with mild intoxication frequently have nausea and vomiting, abdominal pain, lethargy, tinnitus, and dizziness. More significant symptoms occur in more severe poisonings and include hyperthermia, tachypnea, respiratory alkalosis, metabolic acidosis, hyperkalemia, hypoglycemia, hallucinations, confusion, seizure, cerebral edema, and coma. The most common cause of death following an aspirin overdose is cardiopulmonary arrest usually due to pulmonary edema.[80]

    [edit] Toxicity

    The toxic dose of aspirin is generally considered greater than 150 mg per kg of body mass. Moderate toxicity occurs at doses up to 300 mg/kg, severe toxicity occurs between 300 to 500 mg/kg, and a potentially lethal dose is greater than 500 mg/kg.[81] This is the equivalent of many dozens of the common 325 mg tablets, depending on body weight. However children cannot tolerate as much aspirin per unit body weight as adults can.

    [edit] Treatment

    All overdose patients should be conveyed to a hospital for assessment immediately. Initial treatment of an acute overdose includes gastric decontamination. This is achieved by administering activated charcoal, which adsorbs the aspirin in the gastrointestinal tract. Stomach pumps are no longer routinely used in the treatment of poisonings but are sometimes considered if the patient has ingested a potentially lethal amount less than 1 hour previously.[82] Repeated doses of charcoal have been proposed to be beneficial in aspirin overdose;[83] however, one study found that repeat dose charcoal might not be of significant value.[84] However, most toxicologists will administer additional charcoal if serum salicylate levels are increasing.

    Patients are monitored until their peak salicylate blood level has been determined.[85] Blood levels are usually assessed four hours after ingestion and then every two hours after that to determine the maximum level. Maximum levels can be used as a guide to toxic effects expected.[86]

    There is no antidote to salicylate poisoning. Frequent blood work is performed to check metabolic, salicylate, and blood sugar levels; arterial blood gas assessments are performed to test for respiratory alkalosis and metabolic acidosis. Patients are monitored and often treated according to their individual symptoms, patients may be given intravenous potassium chloride to counteract hypokalemia, glucose to restore blood sugar levels, benzodiazepines for any seizure activity, fluids for dehydration, and importantly sodium bicarbonate to restore the blood's sensitive pH balance. Sodium bicarbonate also has the effect of increasing the pH of urine, which in turn increases the elimination of salicylate. Additionally, hemodialysis can be implemented to enhance the removal of salicylate from the blood. Hemodialysis is usually used in severely poisoned patients; for example, patients with significantly high salicylate blood levels, significant neurotoxicity (agitation, coma, convulsions), renal failure, pulmonary edema, or cardiovascular instability are hemodialyzed.[85] Hemodialysis also has the advantage of restoring electrolyte and acid-base abnormalities; hemodialysis is often life-saving in severely ill patients.

  9. basically none, you can't die and your body just can't by overdosed, but if you have hives or swelling your probably allergic.

    oh and aspirin actually is taken to REDUCE the chance of a heart attack, it is wonderful for your heart.

  10. It is SO bad for your heart.

  11. Ringing in the ears (tinnitus) and hearing loss. Too much aspirin (overdosing) can cause tinnitus and eventual hearing loss in some people.

    Hemorrhagic stroke

    Gastrointestinal bleeding

    liver toxicity which can be fatal

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