What exactly does it mean to go "off" yourself?

Question

I have heard and read this expression quite often, and have tolerated it up to the point of which I believe my head will explode, will someone please tell me what this means?

Answer 1

If you off yourself, you kill yourself.

If you go off someone, you no longer like them.

If you off someone, you kill them.

Answer 2

to go commit suicide

Answer 3

suicide