What exactly is the concerta layers?

Question

Im doing a small research product on various ER/TR prescription drugs for ADD/ADHD. What i cant find info on is Concerta. The smaller capsules (i believe 18mg) are small yellow pills. They have 3 sections, White-yellow-grayish :: Which section is the drug? I read that the Grey part is the balance section. But i cant find info on what the yellow or white sections are.

Anyone who knows, thanks a bunch.

Answer 1

Each CONCERTA extended-release tablet contains 18 mg, 27 mg, 36 mg or 54 mg of methylphenidate hydrochloride as the active ingredient.

Each tablet also contains the following other ingredients: butylated hydroxytoluene, carnauba wax, cellulose acetate, hypromellose, Opacode black NS-78-17715, Opadry clear YS-1-19025-A, phosphoric acid, poloxamer, polyethylene oxide, povidone, sodium chloride, stearic acid, succinic acid and synthetic iron oxides.

The 18 mg tablet also contains Opradry II yellow YS-30-12788-A. The 27 mg tablet also contains Opadry II grey Y-30-17528. The 36 mg tablet also contains Opradry II white Y-30-18037. The 54 mg tablet also contains Opradry II red Y-30-15567-A.

CONCERTA extended-release tablets contain

Answer 2

Following oral administration of CONCERTA® XL to adults the drug overcoat dissolves, providing an initial maximum drug concentration at about 1 to 2 hours. The methylphenidate contained in the two internal drug layers is gradually released over the next several hours. Peak plasma concentrations are achieved at about 6 to 8 hours, after which plasma levels of methylphenidate gradually decrease.

Clear Coat: Carnauba wax, Hypromellose 6cp, Macrogol 400

Film Coat: Ferric oxide yellow (E172) (18 mg tablet only), Hypromellose 15cp, Lactose monohydrate, Stearic acid (18 mg tablet only). Titanium dioxide (E171), Triacetin

The inside: Butylhydroxytoluene (E321), Cellulose acetate 398-10, Hypromellose 3cp, Phosphoric acid concentrated, Poloxamer 188, Polyethylene oxides 200K and 7000K, Povidone K29-32, Sodium chloride, Stearic acid, Succinic acid, Black iron oxide (E172), Ferric oxide yellow (E172)