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What helps to stop the bleeding by helping the blood to clot?

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What helps to stop the bleeding by helping the blood to clot?

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  1. the  component called- fibrin { 1 of the factor among blood clotting  contents } will help the blood to clot by forming fibrin threads which bloks larger molecules and prevents them to come out.


  2. elim

  3. a protein in the blood called fibrin.

  4. by drying it so a scab will be formed and it blocks the flowing blood from flowing out of your skin and flesh

  5. I (fibrinogen)- Forms clot (fibrin)

    II (prothrombin)- Its active form (IIa) activates I, V, VIII, XI, XIII, protein C, platelets

    Tissue factor- Co-factor of VIIa (formerly known as factor III)

    Calcium - Required for coagulation factors to bind to phospholipid-(formerly known as factor IV)

    V (proaccelerin, labile factor)- Co-factor of X with which it forms the prothrombinase complex

    VII (stable factor)- Activates IX, X

    VIII (antihemophilic factor)- Co-factor of IX with which it forms the tenase complex

    IX (Christmas factor)- Activates X: forms tenase complex with factor VIII

    X (Stuart-Prower factor)- Activates II: forms prothrombinase complex with factor V

    XI (plasma thromboplastin antecedent)- Activates IX

    XII (Hageman factor)- Activates factor XI and prekallikrein

    XIII (fibrin-stabilizing factor)- Crosslinks fibrin

    von Willebrand factor- Binds to VIII, mediates platelet adhesion

    prekallikrein Activates XII and prekallikrein; -cleaves HMWK

    high molecular weight kininogen (HMWK)- Supports reciprocal activation of XII, XI, and prekallikrein

    fibronectin Mediates cell adhesion

    antithrombin III- Inhibits IIa, Xa, and other proteases;

    heparin cofactor II- Inhibits IIa, cofactor for heparin and dermatan sulfate -("minor antithrombin")

    protein C- Inactivates Va and VIIIa

    protein S- Cofactor for activated protein C (APC, inactive when bound to C4b-binding protein)

    protein Z -Mediates thrombin adhesion to phospholipids and stimulates degradation of factor X by ZPI

    Platelets- adhere to the fibrin and helps form the clot.

    Vitamin K- essential for factors II, VII, IX and X, as well as Protein S, Protein C and Protein Z.

    There are several things involved in the coagulation cascade.

    There is the platelet activation; tissue factor pathway; contact activation pathway; and final common pathway.

  6. Fibrin

    http://en.wikipedia.org/wiki/Fibrin

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